Abstract:The membrane rupture before the process of giving a birth starts can cause health problems. The possible health problems to the fetus can be in the form of a well beingdisorder. This study is aimed to investigate the effect of Sipiritual Endorphine Stimulation on the increasing of the fetus well beingto the mother with the early membrane rupture at Islamic Sultan Agung hospital Semarang. The method The population in this study is the overall pregnant women who experienced premature rupture of membranes. This research used quantitative withpraexperimentalpre post test design with one group on 19 respondents taken by accidental sampling. The intervention was in the form of reciting holy Qur’an, given through auditoric stimulation for 30 minutes.. Data analysis was performed by using wilcoxon test. The result shows that the p value was 0.003. Discussion: auditoric stimulation was accepted by the brain in the Midbrain section, then it stimulated the Midbrain to release Gama Amino Butyric Acid, enkepalin and beta endorphin which function as electrical conductivity inhibitors, have analgesic effect and act as relaxation making the heart rate more regular and the blood circulation run more smoothly. In conclusion there is a significant  effect of Spiritual Endorphin Stimulation on the fetus well beingto the mother with the early membrane rupture

Keywords:Spiritual Endorphin Stimulation, FetalWell Being<span style="