The main aim of this study is to investigate and examine the role of partnership quality in mediating the relationship between communication quality and partnership performance in Islamic hospital industry partnering with BPJS healthcare (Badan Penyelenggara Jaminan Sosial Kesehatan). The sample consists of 88 leaders from 45 Islamic hospitals in Central Java. Data was obtained by distributing questionnaires to the respondents, which were then analyzed using PLS-SEM assisted with the Smart PLS software. The results demonstrate that communication quality has an effect on partnership quality but has no effect on partnership performance. This study also demonstrates that partnership quality has an effect on partnership performance and mediates the relationship between communication quality and partnership performance. Islamic hospitals can enhance the role of partnership quality as a mediator in that relationship. It means for Islamic hospitals to increase partnership performance, the improvement in communication quality must first produce partnership quality.