Innovation is recognized as the basis of competitive organization in this digital era. Leader plays a crucial role in direct the vision and become the role model in the disruption environment. Despite the research on innovation and leadership attract more attention among the scholars, very little empirical research focusing on employee’s spiritual well-being. Innovation that is framed and combined with a spirit of spirituality is important to survive in the disruption era. Spiritual-innovative leadership in this case is a pivotal key as a role model in spiritual-innovation for their employees. This type of leadership is expected to be a driving force in achieving organizational goals in this digital era, employee’s spiritual well-being achievements are not only limited to material well-being, but also spiritual well-being. This article aims to fill up knowledge gap by offering a discussion the relationship between spiritual-innovative leadership and knowledge sharing which has impact on employee’s spiritual well-being.